7S2J

Crystal structure of sulfonamide resistance enzyme Sul2 apoenzyme

7S2J の概要

• エントリーDOI: 10.2210/pdb7s2j/pdb
• 関連するPDBエントリー: 7S2K
• 分子名称: Sul2, SULFATE ION, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: tim barrel, alpha beta protein, antibiotic resistance, sulfonamides, structural genomics, csgid, center for structural genomics of infectious diseases, niaid, national institute of allergy and infectious diseases, transferase
• 由来する生物種: uncultured bacterium
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 115685.37

構造登録者

Stogios, P.J.,Skarina, T.,Michalska, K.,Venkatesan, M.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Biology of Infectious Diseases (CSBID),Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2021-09-03, 公開日: 2023-05-03, 最終更新日: 2023-10-25)

• 主引用文献: Venkatesan, M.,Fruci, M.,Verellen, L.A.,Skarina, T.,Mesa, N.,Flick, R.,Pham, C.,Mahadevan, R.,Stogios, P.J.,Savchenko, A.; Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.; Nat Commun, 14:4031-4031, 2023; PubMed: 37419898; DOI: 10.1038/s41467-023-39778-7

実験手法

X-RAY DIFFRACTION (1.85 Å)