7RXP

Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum

7RXP の概要

• エントリーDOI: 10.2210/pdb7rxp/pdb
• 分子名称: Fab1512 light chain, Fab1512 heavy chain, Circumsporozoite protein, ... (4 entities in total)
• 機能のキーワード: malaria, antibody, sporozoite, circumsporozoite protein, alpha-tsr domain, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 56498.35

構造登録者

Pholcharee, T.,Oyen, D.,Wilson, I.A. (登録日: 2021-08-23, 公開日: 2022-03-16, 最終更新日: 2024-04-03)

• 主引用文献: Beutler, N.,Pholcharee, T.,Oyen, D.,Flores-Garcia, Y.,MacGill, R.S.,Garcia, E.,Calla, J.,Parren, M.,Yang, L.,Volkmuth, W.,Locke, E.,Regules, J.A.,Dutta, S.,Emerling, D.,Early, A.M.,Neafsey, D.E.,Winzeler, E.,King, C.R.,Zavala, F.,Burton, D.R.,Wilson, I.A.,Rogers, T.F.; A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.; Plos Pathog., 18:e1010409-e1010409, 2022; PubMed: 35344575; DOI: 10.1371/journal.ppat.1010409

実験手法

X-RAY DIFFRACTION (1.761 Å)