7RU6
Cryo-EM structure of the HIV-1 restriction factor human SERINC3
Summary for 7RU6
Entry DOI | 10.2210/pdb7ru6/pdb |
EMDB information | 24698 24705 |
Descriptor | Serine incorporator 3, SiA (2 entities in total) |
Functional Keywords | flippase, viral restriction, hiv-1, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 80679.14 |
Authors | Purdy, M.D.,Leonhardt, S.A.,Yeager, M. (deposition date: 2021-08-16, release date: 2022-08-24, Last modification date: 2023-09-06) |
Primary citation | Leonhardt, S.A.,Purdy, M.D.,Grover, J.R.,Yang, Z.,Poulos, S.,McIntire, W.E.,Tatham, E.A.,Erramilli, S.K.,Nosol, K.,Lai, K.K.,Ding, S.,Lu, M.,Uchil, P.D.,Finzi, A.,Rein, A.,Kossiakoff, A.A.,Mothes, W.,Yeager, M. Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry. Nat Commun, 14:4368-4368, 2023 Cited by PubMed: 37474505DOI: 10.1038/s41467-023-39262-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
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