7RTB
Peptide-19 bound to the Glucagon-Like Peptide-1 Receptor (GLP-1R)
Summary for 7RTB
Entry DOI | 10.2210/pdb7rtb/pdb |
EMDB information | 24680 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | glucagon-like peptide-1 receptor (glp-1r), peptide-19 cryo-em, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 163991.76 |
Authors | Johnson, R.M.,Danev, R.,Sexton, P.M.,Wootten, D. (deposition date: 2021-08-12, release date: 2021-10-06) |
Primary citation | Johnson, R.M.,Zhang, X.,Piper, S.J.,Nettleton, T.J.,Vandekolk, T.H.,Langmead, C.J.,Danev, R.,Sexton, P.M.,Wootten, D. Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor. Biochem.Biophys.Res.Commun., 578:84-90, 2021 Cited by PubMed: 34547628DOI: 10.1016/j.bbrc.2021.09.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.14 Å) |
Structure validation
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