7RQX
Cryo-EM structure of the full-length TRPV1 with RTx at 25 degrees Celsius, in an intermediate-open state, class A
Summary for 7RQX
Entry DOI | 10.2210/pdb7rqx/pdb |
EMDB information | 24639 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, ... (5 entities in total) |
Functional Keywords | ligand-gating ion channel, membrane protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 412136.40 |
Authors | |
Primary citation | Kwon, D.H.,Zhang, F.,Fedor, J.G.,Suo, Y.,Lee, S.Y. Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nat Commun, 13:2874-2874, 2022 Cited by PubMed: 35610228DOI: 10.1038/s41467-022-30602-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.36 Å) |
Structure validation
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