7ROL
Amyloid-related segment of alphaB-crystallin residues 90-100 with G95W mutation, bromo derivative
Summary for 7ROL
Entry DOI | 10.2210/pdb7rol/pdb |
Related | 7ROJ |
Descriptor | Alpha-crystallin B chain peptide (1 entity in total) |
Functional Keywords | amyloid oligomer, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 2784.96 |
Authors | Sawaya, M.R.,Do, T.D.,Eisenberg, D.S. (deposition date: 2021-07-30, release date: 2022-02-16, Last modification date: 2022-03-02) |
Primary citation | Gray, A.L.H.,Sawaya, M.R.,Acharyya, D.,Lou, J.,Edington, E.M.,Best, M.D.,Prosser, R.A.,Eisenberg, D.S.,Do, T.D. Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices. Protein Sci., 31:716-727, 2022 Cited by PubMed: 34954854DOI: 10.1002/pro.4268 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.996 Å) |
Structure validation
Download full validation report