7ROL

Amyloid-related segment of alphaB-crystallin residues 90-100 with G95W mutation, bromo derivative

Summary for 7ROL

• Entry DOI: 10.2210/pdb7rol/pdb
• Related: 7ROJ
• Descriptor: Alpha-crystallin B chain peptide (1 entity in total)
• Functional Keywords: amyloid oligomer, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 2784.96

Authors

Sawaya, M.R.,Do, T.D.,Eisenberg, D.S. (deposition date: 2021-07-30, release date: 2022-02-16, Last modification date: 2022-03-02)

• Primary citation: Gray, A.L.H.,Sawaya, M.R.,Acharyya, D.,Lou, J.,Edington, E.M.,Best, M.D.,Prosser, R.A.,Eisenberg, D.S.,Do, T.D.; Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices.; Protein Sci., 31:716-727, 2022; PubMed: 34954854; DOI: 10.1002/pro.4268

Experimental method

X-RAY DIFFRACTION (1.996 Å)