7ROJ

Amyloid-related segment of alphaB-crystallin residues 90-100 with G95W mutation

Summary for 7ROJ

• Entry DOI: 10.2210/pdb7roj/pdb
• Descriptor: Alpha-crystallin B chain peptide, SODIUM ION, trifluoroacetic acid, ... (5 entities in total)
• Functional Keywords: amyloid oligomer, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 12
• Total formula weight: 16526.68

Authors

Sawaya, M.R.,Do, T.D.,Eisenberg, D.S. (deposition date: 2021-07-30, release date: 2022-01-12, Last modification date: 2023-10-18)

• Primary citation: Gray, A.L.H.,Sawaya, M.R.,Acharyya, D.,Lou, J.,Edington, E.M.,Best, M.D.,Prosser, R.A.,Eisenberg, D.S.,Do, T.D.; Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices.; Protein Sci., 31:716-727, 2022; PubMed: 34954854; DOI: 10.1002/pro.4268

Experimental method

X-RAY DIFFRACTION (1.6 Å)