7RNG
Crystal structure of caspase-3 with inhibitor Ac-ITAKD-CHO
Summary for 7RNG
Entry DOI | 10.2210/pdb7rng/pdb |
Descriptor | Caspase-3 subunit p17, Caspase-3 subunit p12, Ac-ITAKD-CHO, ... (4 entities in total) |
Functional Keywords | hydrolase/hydrolase inhibitor, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 55765.80 |
Authors | McCue, W.,Finzel, B.C. (deposition date: 2021-07-29, release date: 2022-06-01, Last modification date: 2024-02-07) |
Primary citation | Bresinsky, M.,Strasser, J.M.,Hubmann, A.,Vallaster, B.,McCue, W.M.,Fuller, J.,Singh, G.,Nelson, K.M.,Cuellar, M.E.,Finzel, B.C.,Ashe, K.H.,Walters, M.A.,Pockes, S. Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis. Arch Pharm, 355:e2200095-e2200095, 2022 Cited by PubMed: 35642311DOI: 10.1002/ardp.202200095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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