7RNG

Crystal structure of caspase-3 with inhibitor Ac-ITAKD-CHO

Summary for 7RNG

• Entry DOI: 10.2210/pdb7rng/pdb
• Descriptor: Caspase-3 subunit p17, Caspase-3 subunit p12, Ac-ITAKD-CHO, ... (4 entities in total)
• Functional Keywords: hydrolase/hydrolase inhibitor, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 55765.80

Authors

McCue, W.,Finzel, B.C. (deposition date: 2021-07-29, release date: 2022-06-01, Last modification date: 2024-02-07)

• Primary citation: Bresinsky, M.,Strasser, J.M.,Hubmann, A.,Vallaster, B.,McCue, W.M.,Fuller, J.,Singh, G.,Nelson, K.M.,Cuellar, M.E.,Finzel, B.C.,Ashe, K.H.,Walters, M.A.,Pockes, S.; Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.; Arch Pharm, 355:e2200095-e2200095, 2022; PubMed: 35642311; DOI: 10.1002/ardp.202200095

Experimental method

X-RAY DIFFRACTION (2.55 Å)