7RM0
Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPG
Summary for 7RM0
Entry DOI | 10.2210/pdb7rm0/pdb |
Descriptor | 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, peptide from Circumsporozoite protein variant VK247, ... (4 entities in total) |
Functional Keywords | antibody, malaria, plasmodium vivax, circumsporozoite protein, antimicrobial protein |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 12 |
Total formula weight | 198240.03 |
Authors | Kucharska, I.,Ivanochko, D.,Julien, J.P. (deposition date: 2021-07-26, release date: 2022-01-26, Last modification date: 2023-10-18) |
Primary citation | Kucharska, I.,Hossain, L.,Ivanochko, D.,Yang, Q.,Rubinstein, J.L.,Pomes, R.,Julien, J.P. Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11:-, 2022 Cited by PubMed: 35023832DOI: 10.7554/eLife.72908 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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