7RKU

Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022

7RKU の概要

• エントリーDOI: 10.2210/pdb7rku/pdb
• 関連するPDBエントリー: 7RKS
• 分子名称: Spike protein S1, C022 Antibody Fab Heavy Chain, C022 Antibody Fab Light Chain, ... (5 entities in total)
• 機能のキーワード: antibody, surface protein, fab, coronavirus, fusion protein, binding domain, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 295991.56

構造登録者

Jette, C.A.,Bjorkman, P.J.,Barnes, C.O. (登録日: 2021-07-22, 公開日: 2021-09-22, 最終更新日: 2023-10-18)

• 主引用文献: Jette, C.A.,Cohen, A.A.,Gnanapragasam, P.N.P.,Muecksch, F.,Lee, Y.E.,Huey-Tubman, K.E.,Schmidt, F.,Hatziioannou, T.,Bieniasz, P.D.,Nussenzweig, M.C.,West Jr., A.P.,Keeffe, J.R.,Bjorkman, P.J.,Barnes, C.O.; Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.; Cell Rep, 36:109760-109760, 2021; PubMed: 34534459; DOI: 10.1016/j.celrep.2021.109760

実験手法

X-RAY DIFFRACTION (3.2 Å)