7RKU

Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Spike protein S1	polymer	212	24004.9	4	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus)
2	E, G, H, J (E, G, H, J)	C022 Antibody Fab Heavy Chain	polymer	240	25978.9	4		Homo sapiens (Human)
3	F, I, K, L (F, I, K, L)	C022 Antibody Fab Light Chain	polymer	215	23610.1	4		Homo sapiens (Human)
4	M, N (M, N)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
5	O, P (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, B, C, D: 328 - 533 (UniProt: P0DTC2)

PDB	External Database	Details
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	294376.1
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	295991.6

*Water molecules are not included.