7RKU
Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Spike protein S1 | polymer | 212 | 24004.9 | 4 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus) | |
2 | E, G, H, J | C022 Antibody Fab Heavy Chain | polymer | 240 | 25978.9 | 4 | Homo sapiens (Human) | ||
3 | F, I, K, L | C022 Antibody Fab Light Chain | polymer | 215 | 23610.1 | 4 | Homo sapiens (Human) | ||
4 | M, N | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
5 | C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 328 - 533 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 294376.1 | |
Branched | Number of molecules | 2 |
Total formula weight | 1173.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 295991.6 |