7RKF

Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state

Summary for 7RKF

• Entry DOI: 10.2210/pdb7rkf/pdb
• EMDB information: 24496
• Descriptor: Guanine nucleotide-binding protein subunit alpha-11, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: viral gpcr, hcmv, cytomegalovirus, g protein complex, gdp-bound state, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 166474.31

Authors

Tsutsumi, N.,Maeda, S.,Qu, Q.,Skiniotis, G.,Kobilka, B.K.,Garcia, K.C. (deposition date: 2021-07-22, release date: 2022-01-26)

• Primary citation: Tsutsumi, N.,Maeda, S.,Qu, Q.,Voegele, M.,Jude, K.M.,Suomivuori, C.M.,Panova, O.,Waghray, D.,Kato, H.E.,Velasco, A.,Dror, R.O.,Skiniotis, G.,Kobilka, B.K.,Garcia, K.C.; Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins; Sci Adv, 8:eabl5442-, 2022; DOI: 10.1126/sciadv.abl5442

Experimental method

ELECTRON MICROSCOPY (4 Å)