7RJP
Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with SHMT
Summary for 7RJP
Entry DOI | 10.2210/pdb7rjp/pdb |
Descriptor | Bromodomain-containing protein 4, Serine hydroxymethyltransferase, cytosolic, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | brd4, shmt, acetyllysine, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 16338.16 |
Authors | Fedorov, E.,Islam, K.,Ghosh, A. (deposition date: 2021-07-21, release date: 2022-08-03, Last modification date: 2023-11-15) |
Primary citation | Wagner, S.,Fedorov, E.,Sudhamalla, B.,Jnawali, H.N.,Debiec, R.,Ghosh, A.,Islam, K. Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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