7RJP

Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with SHMT

Summary for 7RJP

• Entry DOI: 10.2210/pdb7rjp/pdb
• Descriptor: Bromodomain-containing protein 4, Serine hydroxymethyltransferase, cytosolic, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: brd4, shmt, acetyllysine, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 16338.16

Authors

Fedorov, E.,Islam, K.,Ghosh, A. (deposition date: 2021-07-21, release date: 2022-08-03, Last modification date: 2023-11-15)

• Primary citation: Wagner, S.,Fedorov, E.,Sudhamalla, B.,Jnawali, H.N.,Debiec, R.,Ghosh, A.,Islam, K.; Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.25 Å)