7RIX

RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2

7RIX の概要

• エントリーDOI: 10.2210/pdb7rix/pdb
• 分子名称: RNA, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, ... (16 entities in total)
• 機能のキーワード: rna polymerase ii, elongation complex, polyamide, small molecule, transcription, dna binding protein-dna-rna complex, dna binding protein/dna/rna
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 490121.89

構造登録者

Oh, J.,Dervan, P.B.,Wang, D. (登録日: 2021-07-20, 公開日: 2022-01-12, 最終更新日: 2023-10-18)

• 主引用文献: Oh, J.,Jia, T.,Xu, J.,Chong, J.,Dervan, P.B.,Wang, D.; RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder.; Proc.Natl.Acad.Sci.USA, 119:-, 2022; PubMed: 35022237; DOI: 10.1073/pnas.2114065119

実験手法

X-RAY DIFFRACTION (3.4 Å)