7RHM

Structure of Q67H/N74D mutant of disulfide stabilized HIV-1 CA hexamer

Summary for 7RHM

• Entry DOI: 10.2210/pdb7rhm/pdb
• Related: 7RAO 7RAR
• Descriptor: CAPSID PROTEIN P24, IODIDE ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: inhibitor, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 1
• Total formula weight: 26157.16

Authors

Bester, S.M.,Kvaratskhelia, M. (deposition date: 2021-07-17, release date: 2022-07-27, Last modification date: 2023-10-18)

• Primary citation: Bester, S.M.,Adu-Ampratwum, D.,Annamalai, A.S.,Wei, G.,Briganti, L.,Murphy, B.C.,Haney, R.,Fuchs, J.R.,Kvaratskhelia, M.; Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir.; Mbio, 13:e0180422-e0180422, 2022; PubMed: 36190128; DOI: 10.1128/mbio.01804-22

Experimental method

X-RAY DIFFRACTION (2.16 Å)