7RCK
Crystal Structure of PMS2 with Substrate
Summary for 7RCK
Entry DOI | 10.2210/pdb7rck/pdb |
Descriptor | Mismatch repair endonuclease PMS2, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | mismatch repair, variant of uncertain significance, atpase domain, dna repair enzyme, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 82089.43 |
Authors | D'Arcy, B.M.,Prakash, A. (deposition date: 2021-07-07, release date: 2022-03-02, Last modification date: 2023-10-25) |
Primary citation | D'Arcy, B.M.,Arrington, J.,Weisman, J.,McClellan, S.B.,Yang, Z.,Deivanayagam, C.,Blount, J.,Prakash, A. PMS2 variant results in loss of ATPase activity without compromising mismatch repair. Mol Genet Genomic Med, 10:e1908-e1908, 2022 Cited by PubMed: 35189042DOI: 10.1002/mgg3.1908 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
Download full validation report