7RB5
Room temperature structure of hAChE in complex with substrate analog 4K-TMA
Summary for 7RB5
| Entry DOI | 10.2210/pdb7rb5/pdb |
| Descriptor | Acetylcholinesterase, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM (3 entities in total) |
| Functional Keywords | acetylcholine esterase, serine hydrolase, tetrahedral intermediate, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 60450.23 |
| Authors | Kovalevsky, A.,Gerlits, O.,Radic, Z. (deposition date: 2021-07-05, release date: 2021-09-22, Last modification date: 2023-10-18) |
| Primary citation | Gerlits, O.,Blakeley, M.P.,Keen, D.A.,Radic, Z.,Kovalevsky, A. Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure Curr Res Struct Biol, 3:206-215, 2021 Cited by DOI: 10.1016/j.crstbi.2021.08.003PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report
