7RAS

Structure of TRPV3 in complex with osthole

Summary for 7RAS

• Entry DOI: 10.2210/pdb7ras/pdb
• EMDB information: 24385
• Descriptor: Transient receptor potential cation channel subfamily V member 3, 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one (2 entities in total)
• Functional Keywords: trp channel, v3, membrane protein
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 4
• Total formula weight: 371880.48

Authors

Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (deposition date: 2021-07-02, release date: 2021-09-08, Last modification date: 2024-06-05)

• Primary citation: Neuberger, A.,Nadezhdin, K.D.,Zakharian, E.,Sobolevsky, A.I.; Structural mechanism of TRPV3 channel inhibition by the plant-derived coumarin osthole.; Embo Rep., 22:e53233-e53233, 2021; PubMed: 34472684; DOI: 10.15252/embr.202153233

Experimental method

ELECTRON MICROSCOPY (3.64 Å)