7RAS

Structure of TRPV3 in complex with osthole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Transient receptor potential cation channel subfamily V member 3	polymer	808	92481.5	4	UniProt (Q8K424) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) In PDB	Mus musculus (Mouse)	TrpV3
2	A, B, C, D	7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one	non-polymer		244.3	8	Chemie (A0O)

Sequence modifications

A, B, C, D: 1 - 791 (UniProt: Q8K424)

PDB	External Database	Details
Gly 2	Asn 2	conflict
Ala 564	Tyr 564	engineered mutation
Leu 792	-	expression tag
Val 793	-	expression tag
Pro 794	-	expression tag
Arg 795	-	expression tag
Gly 796	-	expression tag
Ser 797	-	expression tag
Ala 798	-	expression tag
Ala 799	-	expression tag
Ala 800	-	expression tag
Trp 801	-	expression tag
Ser 802	-	expression tag
His 803	-	expression tag
Pro 804	-	expression tag
Gln 805	-	expression tag
Phe 806	-	expression tag
Glu 807	-	expression tag
Lys 808	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	369926.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1954.3
All*	Total formula weight	371880.5

*Water molecules are not included.