7RA0
LC3A in complex with Fragment 2-10
Summary for 7RA0
Entry DOI | 10.2210/pdb7ra0/pdb |
Descriptor | Microtubule-associated proteins 1A/1B light chain 3A, (5-ethyl-2-methyl-1H-indol-3-yl)acetic acid (3 entities in total) |
Functional Keywords | matg8, autophagy, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14724.93 |
Authors | Rouge, L.,Steffek, M.,Helgason, E.,Dueber, E.,Mulvihill, M. (deposition date: 2021-06-29, release date: 2022-01-12, Last modification date: 2023-10-25) |
Primary citation | Steffek, M.,Helgason, E.,Popovych, N.,Rouge, L.,Bruning, J.M.,Li, K.S.,Burdick, D.J.,Cai, J.,Crawford, T.,Xue, J.,Decurtins, W.,Fang, C.,Grubers, F.,Holliday, M.J.,Langley, A.,Petersen, A.,Satz, A.L.,Song, A.,Stoffler, D.,Strebel, Q.,Tom, J.Y.K.,Skelton, N.,Staben, S.T.,Wichert, M.,Mulvihill, M.M.,Dueber, E.C. A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands. Biochemistry, 62:633-644, 2023 Cited by PubMed: 34985287DOI: 10.1021/acs.biochem.1c00682 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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