7R9F

Wild-type yeast Pseudouridine Synthase, PUS1, bound to 5-Fluorouracil RNA

Summary for 7R9F

• Entry DOI: 10.2210/pdb7r9f/pdb
• Descriptor: tRNA pseudouridine synthase 1, RNA (5'-R(*UP*AP*AP*UP*CP*GP*GP*GP*AP*UP*UP*CP*CP*GP*GP*AP*UP*A)-3'), SULFATE ION (3 entities in total)
• Functional Keywords: pseudouridine, pus, pus1, rna, synthase, mrna, yeast, pseudo uracil, pseudouracil, uracil, saccharomyces cerevisiae, inactive, catalytically inactive, dead, pseudouridine synthase, rna binding protein, 5-fluorouracil, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 68049.11

Authors

Doyle, L.A.,Stoddard, B.L. (deposition date: 2021-06-29, release date: 2021-12-15, Last modification date: 2023-11-15)

• Primary citation: Grunberg, S.,Doyle, L.A.,Wolf, E.J.,Dai, N.,Correa Jr., I.R.,Yigit, E.,Stoddard, B.L.; The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1.; Plos One, 18:e0291267-e0291267, 2023; PubMed: 37939088; DOI: 10.1371/journal.pone.0291267

Experimental method

X-RAY DIFFRACTION (2.89 Å)