7R8U
LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis
This is a non-PDB format compatible entry.
Summary for 7R8U
Entry DOI | 10.2210/pdb7r8u/pdb |
Descriptor | Oxidized low-density lipoprotein receptor 1, Antigen binding fragment, Vh and Ch1, Antibody light chain, kappa, ... (5 entities in total) |
Functional Keywords | low density lipoprotein receptor antibody complex lox-1 scavenger receptor atherogenesis-atherosclerosis macrophage cardiovascular disease, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 77981.45 |
Authors | Oganesyan, V.,van Dyk, N. (deposition date: 2021-06-27, release date: 2022-06-01, Last modification date: 2023-11-29) |
Primary citation | Ongstad, E.L.,Gaddipati, R.,Belkhodja, M.,van Dyk, N.,Levy, S.,Sagar, D.,Cariuk, P.,Wolny, M.,Hanna, R.N.,Borrok, M.J.,Buchanan, A.,Oganesyan, V.,Gupta, R. Structural and functional studies of a monoclonal antibody blocking LOX-1 Commun Med, 2023 |
Experimental method | X-RAY DIFFRACTION (1.901 Å) |
Structure validation
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