7R4N

Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide

Summary for 7R4N

• Entry DOI: 10.2210/pdb7r4n/pdb
• Related: 5qib 5qic 5qid 5qie 5qif 5qig 5qih
• Descriptor: Hydroxyacid oxidase 1, 1,2-ETHANEDIOL, 5-bromanyl-N-methyl-1H-indazole-3-carboxamide, ... (5 entities in total)
• Functional Keywords: hao1, hydroxyacid oxidase, glycolate oxidase, fragment screening, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40924.75

Authors

Mackinnon, S.,Bezerra, G.A.,Krojer, T.,Bradley, A.R.,Talon, R.,Brandeo-Neto, J.,Douangamath, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Oppermann, U.,Brennan, P.E.,Yue, W.W. (deposition date: 2022-02-08, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Mackinnon, S.,Bezerra, G.A.,Krojer, T.,Bradley, A.R.,Talon, R.,Brandeo-Neto, J.,Douangamath, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Oppermann, U.,Brennan, P.E.,Yue, W.W.; Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)