7R2V
Structure of nsp14 from SARS-CoV-2 in complex with SAH
Summary for 7R2V
Entry DOI | 10.2210/pdb7r2v/pdb |
Descriptor | Proofreading exoribonuclease nsp14, S-ADENOSYL-L-HOMOCYSTEINE, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | nsp14, complex, sah, sars-cov-2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 2 |
Total formula weight | 120617.99 |
Authors | Czarna, A.,Plewka, J.,Kresik, L.,Matsuda, A.,Abdulkarim, K.,Robinson, C.,OByrne, S.,Cunningham, F.,Georgiou, I.,Pachota, M.,Popowicz, G.M.,Wyatt, P.G.,Dubin, G.,Pyrc, K. (deposition date: 2022-02-06, release date: 2022-03-09, Last modification date: 2024-01-31) |
Primary citation | Czarna, A.,Plewka, J.,Kresik, L.,Matsuda, A.,Karim, A.,Robinson, C.,O'Byrne, S.,Cunningham, F.,Georgiou, I.,Wilk, P.,Pachota, M.,Popowicz, G.,Wyatt, P.G.,Dubin, G.,Pyrc, K. Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity. Structure, 30:1050-1054.e2, 2022 Cited by PubMed: 35609600DOI: 10.1016/j.str.2022.04.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.53 Å) |
Structure validation
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