7QXD

Recognition of Staphylococcus aureus wall teichoic acid analogue SA475 (compound 2) by Fab4497

This is a non-PDB format compatible entry.

Summary for 7QXD

• Entry DOI: 10.2210/pdb7qxd/pdb
• Descriptor: Antibody Fab 4497 heavy chain, Antibody Fab 4497 light chain, [(2~{S},3~{S},4~{R})-4-[(2~{S},3~{R},4~{R},5~{S},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-5-[[(2~{S},3~{R})-2,3-bis(oxidanyl)butoxy]-oxidanyl-phosphoryl]oxy-2,3-bis(oxidanyl)pentyl] [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] hydrogen phosphate, ... (7 entities in total)
• Functional Keywords: antibody, fab fragment, teichoic acid analogue, carbohydrate
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 100803.37

Authors

Soriano-Maldonado, P.,van Raaij, M.J. (deposition date: 2022-01-26, release date: 2022-08-31, Last modification date: 2024-01-31)

• Primary citation: Di Carluccio, C.,Soriano-Maldonado, P.,Berni, F.,de Haas, C.J.C.,Temming, A.R.,Hendriks, A.,Ali, S.,Molinaro, A.,Silipo, A.,van Sorge, N.M.,van Raaij, M.J.,Codee, J.D.C.,Marchetti, R.; Antibody Recognition of Different Staphylococcus aureus Wall Teichoic Acid Glycoforms.; Acs Cent.Sci., 8:1383-1392, 2022; PubMed: 36313161; DOI: 10.1021/acscentsci.2c00125

Experimental method

X-RAY DIFFRACTION (1.649 Å)