7QXB
Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)
Summary for 7QXB
Entry DOI | 10.2210/pdb7qxb/pdb |
Related | 7QXA 7QXS |
EMDB information | 14196 14197 14198 14199 |
Descriptor | Telomerase reverse transcriptase, human telomerase RNA, Histone H2A, ... (7 entities in total) |
Functional Keywords | reverse transcriptase, ribonucleoprotein, telomerase, telomere, dna binding protein, rna binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 434924.07 |
Authors | Sekne, Z.,Ghanim, G.E.,van Roon, A.M.M.,Nguyen, T.H.D. (deposition date: 2022-01-26, release date: 2022-03-02, Last modification date: 2022-03-23) |
Primary citation | Sekne, Z.,Ghanim, G.E.,van Roon, A.M.,Nguyen, T.H.D. Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375:1173-1176, 2022 Cited by PubMed: 35201900DOI: 10.1126/science.abn6840 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.91 Å) |
Structure validation
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