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7QXB

Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Telomerase reverse transcriptasepolymer1132127195.81UniProt (O14746)
Pfam (PF12009)
Pfam (PF21399)
Homo sapiens (human)HEST2,Telomerase catalytic subunit,Telomerase-associated protein 2,TP2
2B
(B)
human telomerase RNApolymer451145477.81GenBank (NR_001566)Homo sapiens (human)
3C
(L)
Histone H2Apolymer13014140.61UniProt (B2R5B3)Homo sapiens (human)
4D
(M)
Histone H2Bpolymer16618074.91UniProt (B4DR52)Homo sapiens (human)
5E
(N)
Telomeric DNApolymer309501.11Homo sapiens
6F
(O)
Adrenocortical dysplasia homolog (Mouse), isoform CRA_apolymer45849013.11UniProt (A0A590TQL1)
Pfam (PF10341)
UniProt (by SIFTS) (Q96AP0)
Homo sapiens (human)Adrenocortical dysplasia protein homolog
7G
(P)
Protection of telomeres protein 1polymer63471520.81UniProt (Q9NUX5)
Pfam (PF02765)
Pfam (PF16686)
Pfam (PF21375)
Homo sapiens (human)hPot1,POT1-like telomere end-binding protein
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight434924.1
All*Total formula weight434924.1
*Water molecules are not included.

250359

PDB entries from 2026-03-11

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