7QVN

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with(1H-pyrazol-5-yl)methanol

Summary for 7QVN

Entry DOI	10.2210/pdb7qvn/pdb
Descriptor	Cholinephosphate cytidylyltransferase, 1~{H}-pyrazol-5-ylmethanol, Guanidinium, ... (4 entities in total)
Functional Keywords	plasmodium falciparum cct inhibitors fragments, transferase
Biological source	Plasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains	1
Total formula weight	21028.38
Authors	Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2022-01-22, release date: 2023-01-25, Last modification date: 2024-02-07)
Primary citation	Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published,
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation