7QVM

Human Oxytocin receptor (OTR) oxytocin Gq chimera (mGoqi) complex

Summary for 7QVM

Entry DOI	10.2210/pdb7qvm/pdb
EMDB information	14180
Descriptor	Guanine nucleotide-binding protein G(o) subunit alpha,cDNA FLJ31446 fis, clone NT2NE2000909, highly similar to Guanine nucleotide-binding protein G(o) subunit alpha 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	gpcr, otr, g protein, ot, scfv16, mgoqi, oxytocin, membrane protein, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	140063.41
Authors	Waltenspuhl, Y.,Ehrenmann, J.,Vacca, S.,Thom, C.,Medalia, O.,Pluckthun, A. (deposition date: 2022-01-21, release date: 2022-08-10)
Primary citation	Waltenspuhl, Y.,Ehrenmann, J.,Vacca, S.,Thom, C.,Medalia, O.,Pluckthun, A. Structural basis for the activation and ligand recognition of the human oxytocin receptor. Nat Commun, 13:4153-4153, 2022 Cited by PubMed: 35851571 DOI: 10.1038/s41467-022-31325-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.25 Å)

Structure validation