7QSI
human Carbonic Anhydrase II in complex with indoline-1-sulfonamide
This is a non-PDB format compatible entry.
Summary for 7QSI
| Entry DOI | 10.2210/pdb7qsi/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | carbonic anhydrase ii, inhibitor, metalloenzime, sulfonamide, lyase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29644.81 |
| Authors | Angeli, A.,Ferraroni, M. (deposition date: 2022-01-13, release date: 2023-01-25, Last modification date: 2024-02-07) |
| Primary citation | Sharonova, T.,Zhmurov, P.,Kalinin, S.,Nocentini, A.,Angeli, A.,Ferraroni, M.,Korsakov, M.,Supuran, C.T.,Krasavin, M. Diversely substituted sulfamides for fragment-based drug discovery of carbonic anhydrase inhibitors: synthesis and inhibitory profile. J Enzyme Inhib Med Chem, 37:857-865, 2022 Cited by PubMed: 35296197DOI: 10.1080/14756366.2022.2051023 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.304 Å) |
Structure validation
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