7QPP
High resolution structure of human VDR ligand binding domain in complex with calcitriol
Summary for 7QPP
Entry DOI | 10.2210/pdb7qpp/pdb |
Descriptor | Vitamin D3 receptor, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | vdr, calcitriol, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 30318.04 |
Authors | Rochel, N. (deposition date: 2022-01-05, release date: 2022-12-28, Last modification date: 2024-01-31) |
Primary citation | Sigueiro, R.,Bianchetti, L.,Peluso-Iltis, C.,Chalhoub, S.,Dejaegere, A.,Osz, J.,Rochel, N. Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain. J.Med.Chem., 65:5821-5829, 2022 Cited by PubMed: 35302785DOI: 10.1021/acs.jmedchem.2c00171 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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