7QO1

complex of DNA ligase I and FEN1 on PCNA and DNA

Summary for 7QO1

• Entry DOI: 10.2210/pdb7qo1/pdb
• EMDB information: 14080
• Descriptor: DNA ligase 1, Proliferating cell nuclear antigen, Oligo19ddC, ... (7 entities in total)
• Functional Keywords: dna, replication, complex, ligase, pcna, ligation, fen1, flap endonuclease i, okazaki fragment maturation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 234101.69

Authors

Blair, K.,Tehseen, M.,Raducanu, V.S.,Shahid, T.,Lancey, C.,Cruehet, R.,Hamdan, S.,De Biasio, A. (deposition date: 2021-12-23, release date: 2023-01-11)

• Primary citation: Blair, K.,Tehseen, M.,Raducanu, V.S.,Shahid, T.,Lancey, C.,Rashid, F.,Creuhet, R.,Hamdan, S.M.,De Biasio, A.; Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.; Nat Commun, 13:7833-7833, 2022; PubMed: 36539424; DOI: 10.1038/s41467-022-35475-z

Experimental method

ELECTRON MICROSCOPY (4.4 Å)