7QL5

Torpedo muscle-type nicotinic acetylcholine receptor - nicotine-bound conformation

Summary for 7QL5

• Entry DOI: 10.2210/pdb7ql5/pdb
• Related: 7QKO
• EMDB information: 14064
• Descriptor: Acetylcholine receptor subunit alpha, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: pentameric ligand-gated ion channel, nicotinic receptor, membrane protein
• Biological source: Tetronarce californica (Pacific electric ray); More
• Total number of polymer chains: 5
• Total formula weight: 283473.91

Authors

Zarkadas, E.,Pebay-Peyroula, E.,Baenziger, J.,Nury, H. (deposition date: 2021-12-19, release date: 2022-02-09, Last modification date: 2022-05-04)

• Primary citation: Zarkadas, E.,Pebay-Peyroula, E.,Thompson, M.J.,Schoehn, G.,Uchanski, T.,Steyaert, J.,Chipot, C.,Dehez, F.,Baenziger, J.E.,Nury, H.; Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor.; Neuron, 110:1358-, 2022; PubMed: 35139364; DOI: 10.1016/j.neuron.2022.01.013

Experimental method

ELECTRON MICROSCOPY (2.5 Å)