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7QK9

Crystal structure of the ALDH1A3-ATP complex

Summary for 7QK9
Entry DOI10.2210/pdb7qk9/pdb
DescriptorAldehyde dehydrogenase family 1 member A3, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (7 entities in total)
Functional Keywordsaldh1a3, aldehyde dehydrogenase family 1 member a3, atp, oxidoreductase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight110087.33
Authors
Castellvi, A.,Farres, J. (deposition date: 2021-12-17, release date: 2022-04-20, Last modification date: 2024-01-31)
Primary citationCastellvi, A.,Pequerul, R.,Barracco, V.,Juanhuix, J.,Pares, X.,Farres, J.
Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3.
Commun Biol, 5:354-354, 2022
Cited by
PubMed: 35418200
DOI: 10.1038/s42003-022-03311-1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.782 Å)
Structure validation

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