7QGV
Solid-state NMR structure of Teixobactin-Lipid II.
Summary for 7QGV
Entry DOI | 10.2210/pdb7qgv/pdb |
NMR Information | BMRB: 50938 |
Related PRD ID | PRD_002268 PRD_002384 |
Descriptor | Teixobactin, Lipid II, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ... (5 entities in total) |
Functional Keywords | antimicrobial, beta-sheet, membrane deformation, antibiotic |
Biological source | Eleftheria terrae More |
Total number of polymer chains | 8 |
Total formula weight | 10659.38 |
Authors | Weingarth, M.H.,Shukla, R. (deposition date: 2021-12-10, release date: 2022-08-03, Last modification date: 2023-11-15) |
Primary citation | Shukla, R.,Lavore, F.,Maity, S.,Derks, M.G.N.,Jones, C.R.,Vermeulen, B.J.A.,Melcrova, A.,Morris, M.A.,Becker, L.M.,Wang, X.,Kumar, R.,Medeiros-Silva, J.,van Beekveld, R.A.M.,Bonvin, A.M.J.J.,Lorent, J.H.,Lelli, M.,Nowick, J.S.,MacGillavry, H.D.,Peoples, A.J.,Spoering, A.L.,Ling, L.L.,Hughes, D.E.,Roos, W.H.,Breukink, E.,Lewis, K.,Weingarth, M. Teixobactin kills bacteria by a two-pronged attack on the cell envelope. Nature, 608:390-396, 2022 Cited by PubMed: 35922513DOI: 10.1038/s41586-022-05019-y PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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