7QGP

STK10 (LOK) bound to Macrocycle CKJB51

7QGP の概要

• エントリーDOI: 10.2210/pdb7qgp/pdb
• 分子名称: Serine/threonine-protein kinase 10, 1-[(4-chloranyl-2-methyl-phenyl)methyl]-3-(7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl)urea, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: kinase, stk10, lok, macrocycle, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34830.98

構造登録者

Berger, B.-T.,Schroeder, M.,Kraemer, A.,Schwalm, M.P.,Kurz, C.G.,Amrhein, J.A.,Hanke, T.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2021-12-09, 公開日: 2022-01-26, 最終更新日: 2024-01-31)

• 主引用文献: Schroeder, M.,Berger, B.T.,Kraemer, A.,Kurz, C.G.,Amrhein, J.A.,Hanke, T.,Knapp, S.,Structural Genomics Consortium (SGC); STK10 bound to CKJB51; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)