7QF0
Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325
Summary for 7QF0
Entry DOI | 10.2210/pdb7qf0/pdb |
Descriptor | Spike protein S1, CV2.2325 heavy chain, CV2.2325 light chain, ... (7 entities in total) |
Functional Keywords | neutralization, antibody, coronavirus, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 3 |
Total formula weight | 71499.75 |
Authors | Fernandez, I.,Pederzoli, R.,Rey, F.A. (deposition date: 2021-12-03, release date: 2022-05-18, Last modification date: 2024-02-07) |
Primary citation | Planchais, C.,Fernandez, I.,Bruel, T.,de Melo, G.D.,Prot, M.,Beretta, M.,Guardado-Calvo, P.,Dufloo, J.,Molinos-Albert, L.M.,Backovic, M.,Chiaravalli, J.,Giraud, E.,Vesin, B.,Conquet, L.,Grzelak, L.,Planas, D.,Staropoli, I.,Guivel-Benhassine, F.,Hieu, T.,Boulle, M.,Cervantes-Gonzalez, M.,Ungeheuer, M.N.,Charneau, P.,van der Werf, S.,Agou, F.,Dimitrov, J.D.,Simon-Loriere, E.,Bourhy, H.,Montagutelli, X.,Rey, F.A.,Schwartz, O.,Mouquet, H. Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219:-, 2022 Cited by PubMed: 35704748DOI: 10.1084/jem.20220638 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report