7QEZ

Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022

Summary for 7QEZ

Entry DOI	10.2210/pdb7qez/pdb
Descriptor	Spike protein S1, CR3022 heavy chain, CR3022 light chain, ... (8 entities in total)
Functional Keywords	neutralization, antibody, coronavirus, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	5
Total formula weight	119796.34
Authors	Fernandez, I.,Rey, F.A. (deposition date: 2021-12-03, release date: 2022-05-18, Last modification date: 2024-02-07)
Primary citation	Planchais, C.,Fernandez, I.,Bruel, T.,de Melo, G.D.,Prot, M.,Beretta, M.,Guardado-Calvo, P.,Dufloo, J.,Molinos-Albert, L.M.,Backovic, M.,Chiaravalli, J.,Giraud, E.,Vesin, B.,Conquet, L.,Grzelak, L.,Planas, D.,Staropoli, I.,Guivel-Benhassine, F.,Hieu, T.,Boulle, M.,Cervantes-Gonzalez, M.,Ungeheuer, M.N.,Charneau, P.,van der Werf, S.,Agou, F.,Dimitrov, J.D.,Simon-Loriere, E.,Bourhy, H.,Montagutelli, X.,Rey, F.A.,Schwartz, O.,Mouquet, H. Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219:-, 2022 Cited by PubMed: 35704748 DOI: 10.1084/jem.20220638 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.89 Å)

Structure validation