7QC2

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT334 and L-Proline

7QC2 の概要

• エントリーDOI: 10.2210/pdb7qc2/pdb
• 分子名称: Proline--tRNA ligase, PROLINE, ~{N}-(2,3-dihydro-1~{H}-inden-2-yl)-3-[[4-[[(2~{S})-pyrrolidin-2-yl]carbonylamino]piperidin-1-yl]carbonylamino]pyrazine-2-carboxamide, ... (5 entities in total)
• 機能のキーワード: proline, aminoacyl-trna synthetase, ligase, protein biosynthesis
• 由来する生物種: Plasmodium falciparum (isolate 3D7)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 59305.82

構造登録者

Johansson, C.,Tye, M.,Payne, N.C.,Mazitschek, R.,Oppermann, U.C.T. (登録日: 2021-11-22, 公開日: 2022-05-04, 最終更新日: 2024-01-31)

• 主引用文献: Johansson, C.,Tye, M.,Payne, N.C.,Mazitschek, R.,Oppermann, U.C.T.; Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT334 and L-Proline; To Be Published,

実験手法

X-RAY DIFFRACTION (2.28 Å)