7Q6N

Structure of WrbA from Salmonella Typhimurium bound to ME0052

Summary for 7Q6N

Entry DOI	10.2210/pdb7q6n/pdb
Descriptor	NAD(P)H dehydrogenase (quinone), 2-azanyl-4,6-bis(bromanyl)phenol, FLAVIN MONONUCLEOTIDE, ... (5 entities in total)
Functional Keywords	nadh dehydrogenase, oxidoreductase, flavoprotein, anti-virulence compound
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Total number of polymer chains	4
Total formula weight	101790.41
Authors	Gabrielsen, M.,Beckham, K.S.H.,Roe, A.J. (deposition date: 2021-11-08, release date: 2022-08-03, Last modification date: 2024-01-31)
Primary citation	Zambelloni, R.,Beckham, K.S.H.,Wu, H.J.,Elofsson, M.,Marquez, R.,Gabrielsen, M.,Roe, A.J. Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds. Microbiology (Reading, Engl.), 168:-, 2022 Cited by PubMed: 35829699 DOI: 10.1099/mic.0.001211 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation