7Q6C
complement C6 FIM1-2 bound to CP010 antibody
Summary for 7Q6C
Entry DOI | 10.2210/pdb7q6c/pdb |
Descriptor | Complement component C6, CP010 heavy chain, kappa specific nanobody, ... (6 entities in total) |
Functional Keywords | complement antibody terminal pathway, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 79254.31 |
Authors | Olesen, H.G.,Andersen, G.R. (deposition date: 2021-11-06, release date: 2022-05-25, Last modification date: 2024-01-31) |
Primary citation | Gytz Olesen, H.,Michailidou, I.,Zelek, W.M.,Vreijling, J.,Ruizendaal, P.,de Klein, F.,Marquart, J.A.,Kuipers, T.B.,Mei, H.,Zhang, Y.,Ahasan, M.,Johnson, K.K.,Wang, Y.,Morgan, B.P.,van Dijk, M.,Fluiter, K.,Andersen, G.R.,Baas, F. Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex. J Innate Immun, :1-21, 2022 Cited by PubMed: 35551129DOI: 10.1159/000524587 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29274 Å) |
Structure validation
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