7Q5U
The tandem SH2 domains of SYK with a bound CD3G diphospho-ITAM peptide
This is a non-PDB format compatible entry.
Summary for 7Q5U
Entry DOI | 10.2210/pdb7q5u/pdb |
Descriptor | Tyrosine-protein kinase SYK, T-cell surface glycoprotein CD3 gamma chain, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | signalling, kinase, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 196170.33 |
Authors | Bradshaw, W.J.,Katis, V.L.,Chen, Z.,Bountra, C.,von Delft, F.,Gileadi, O.,Brennan, P.E. (deposition date: 2021-11-04, release date: 2021-11-24, Last modification date: 2024-01-31) |
Primary citation | Bradshaw, W.J.,Katis, V.L.,Chen, Z.,Bountra, C.,von Delft, F.,Gileadi, O.,Brennan, P.E. The tandem SH2 domains of SYK To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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