7Q4I

Crystal structure of DmC1GalT1 in complex with UDP-Mn2+ and the APD-TGalNAc-RP

7Q4I の概要

• エントリーDOI: 10.2210/pdb7q4i/pdb
• 分子名称: Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, Mucin-1, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: c1galt1, t-synthase, t antigen, tn antigen, mucin-type o-glycosylation, transferase
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75389.86

構造登録者

Gonzalez-Ramirez, A.M.,Coelho, H.,Companon, I.,Grosso, A.S.,Yang, Z.,Narimatsu, Y.,Clausen, H.,Marcelo, F.,Corzana, F.,Hurtado-Guerrero, R. (登録日: 2021-10-31, 公開日: 2022-04-13, 最終更新日: 2024-05-01)

• 主引用文献: Gonzalez-Ramirez, A.M.,Grosso, A.S.,Yang, Z.,Companon, I.,Coelho, H.,Narimatsu, Y.,Clausen, H.,Marcelo, F.,Corzana, F.,Hurtado-Guerrero, R.; Structural basis for the synthesis of the core 1 structure by C1GalT1.; Nat Commun, 13:2398-2398, 2022; PubMed: 35504880; DOI: 10.1038/s41467-022-29833-0

実験手法

X-RAY DIFFRACTION (2.4 Å)