7Q3M

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 3-hydroxypiperidine

Summary for 7Q3M

Entry DOI	10.2210/pdb7q3m/pdb
Descriptor	Cholinephosphate cytidylyltransferase, Guanidinium, (3S)-piperidin-3-ol, ... (4 entities in total)
Functional Keywords	plasmodium falciparum cct inhibitors fragments, transferase
Biological source	Plasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains	1
Total formula weight	21293.80
Authors	Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-10-28, release date: 2022-11-09, Last modification date: 2024-01-31)
Primary citation	Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors. To Be Published,
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation