7Q2M

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with but-3-yn-2-amine hydrochloride

Summary for 7Q2M

• Entry DOI: 10.2210/pdb7q2m/pdb
• Descriptor: Cholinephosphate cytidylyltransferase, (2S)-but-3-yn-2-amine (3 entities in total)
• Functional Keywords: plasmodium falciparum cct inhibitors fragments, transferase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 1
• Total formula weight: 20948.33

Authors

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.F. (deposition date: 2021-10-25, release date: 2022-11-23, Last modification date: 2024-01-31)

• Primary citation: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.08 Å)