7Q2I

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with Tetrahydrofurfurylamine

Summary for 7Q2I

Entry DOI	10.2210/pdb7q2i/pdb
Descriptor	Cholinephosphate cytidylyltransferase, 1-[(2R)-oxolan-2-yl]methanamine, Guanidinium, ... (4 entities in total)
Functional Keywords	plasmodium falciparum cct inhibitors fragments, transferase
Biological source	Plasmodium falciparum
Total number of polymer chains	1
Total formula weight	21072.50
Authors	Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-10-25, release date: 2022-11-09, Last modification date: 2024-01-31)
Primary citation	Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published,
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation