7Q2B

mycolic acid methyltransferase Hma (MmaA4) from Mycobac-terium tuberculosis in complex with ZT218

Summary for 7Q2B

Entry DOI	10.2210/pdb7q2b/pdb
Related	7Q2C 7Q2D 7Q2E 7Q2F 7Q2G 7Q2H
Descriptor	Hydroxymycolate synthase MmaA4, 2-(phenylmethyl)imidazolidine, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywords	mycolic acid methyltransferase mycobacterium tuberculosis fragment based ligand discovery, transferase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	1
Total formula weight	36966.55
Authors	Maveyraud, L.,Galy, R.,Mourey, L. (deposition date: 2021-10-25, release date: 2022-02-02, Last modification date: 2024-01-31)
Primary citation	Galy, R.,Ballereau, S.,Genisson, Y.,Mourey, L.,Plaquevent, J.C.,Maveyraud, L. Fragment-Based Ligand Discovery Applied to the Mycolic Acid Methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis : A Crystallographic and Molecular Modelling Study. Pharmaceuticals, 14:-, 2021 Cited by PubMed: 34959681 DOI: 10.3390/ph14121282 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation