7Q02

Zn-free structure of lipocalin-like Milk protein, inspired from Diploptera punctata, expressed in Saccharomyces cerevisiae

Summary for 7Q02

Entry DOI	10.2210/pdb7q02/pdb
Related	7BKX
Descriptor	Milk protein, PALMITOLEIC ACID (3 entities in total)
Functional Keywords	lipocalin, milk protein, dipolptera punctata, lipid binding protein
Biological source	Diploptera punctata (Pacific beetle cockroach)
Total number of polymer chains	1
Total formula weight	19107.68
Authors	Banerjee, S.,Dhanabalan, K.V.,Ramaswamy, S. (deposition date: 2021-10-14, release date: 2021-12-22, Last modification date: 2024-11-13)
Primary citation	KanagaVijayan, D.,Subramanian, R.,Santhakumari, P.R.,Chavas, L.M.G.,Banerjee, S. Structure of recombinantly expressed cockroach Lili-Mip protein in glycosylated and deglycosylated forms. Biochim Biophys Acta Gen Subj, 1866:130064-130064, 2022 Cited by PubMed Abstract: The Pacific Beetle Cockroach is the only known viviparous cockroach. The pregnant females provide nutrition to the embryos by secreting milk proteins (Lili-Mips), which crystallize in vivo. The crystals that grow in the embryo are heterogeneous in their protein sequence. It is not apparent from the structure determined what role heterogeneity and glycosylation played in crystallization. Lili-Mips are very nutritious. PubMed: 34958847 DOI: 10.1016/j.bbagen.2021.130064 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation